Although frowned upon for being a partaker in the multitude of tobacco-caused fatalities reported each year, nicotine in freebase form can have remarkable effects on the body; most, if not all of them being remedially beneficial.
Nicotine, in and of itself, does not cause disease. One of nicotine’s metabolites, cotinine, improves memory and protects brain cells from diseases such as Alzheimer’s and Parkinson’s according to a recent government study. Alzheimer’s disease is caused by a loss of nicotinic receptors in the brain resulting acetylcholine deficiency. Without the chemical acetylcholine, the brain’s memory function becomes impaired and numerous other adverse mental conditions develop. By artificially replacing acetylcholine through nicotine therapy, the damaging effects of Alzheimer’s diseases on the brain are inhibited. These findings are recent and still undergoing research to develop more sophisticated treatment methods. Experimental treatment of genetically modified rats has proven to be incredibly successful, but nicotine therapy may take years until endorsed by medical authorities and utilized as a known treatment option.
Individuals suffering from hypothyroidism may also benefit from nicotine’s remarkable remedial effects that can help alleviate some of the learning and memory problems associated with the condition. Acetylcholine, the chemical responsible for the brains memory and learning capabilities can be supplemented by nicotine and restore the brain to a normal functional state. Individuals coping with attention deficit disorder (ADD) may also find nicotine of great medicinal value to restrain the symptoms of the condition. The trafficking of dopamine, norepinephrine, 5-hydroxytryptamine, and gamma-aminobutyric acid via pathways between the nicotinic acetylcholine receptors and noncholinergic neuronal subtypes creates an intensive attentional and antidepressant response whilst effectively suppressing the symptoms associated with ADD. Following a successful subject study, James A. Cocores, MD along with various other researchers affirm that nicotine therapy is a highly effective treatment for ADD. As previously noted, its interaction with the brain’s neurochemical structure warrants it an ultra-effective approach in subduing ADD’s disparaging symptoms eliquid
Nicotine has also been proven to be effective in repairing veins and promoting the development of new blood vessels in mice and humans. As study led by John P. Cooke, MD reveals that “when nicotine binds to the receptor on endothelial cells it stimulates the cells to release a cascade of chemicals that promote the formation of new blood vessels” and “nicotine enhanced the vascularization of discs implanted under the skin of mice as well as another naturally occurring compound, known as fibroblast growth factor… which frequently stimulates new blood vessel growth.” However, nicotine is such a powerful mediator in angiogenesis (production of new blood vessels) that it can enlarge tumors in subjects with pre-existing cancer. Once a proven and safe therapy protocol has been established, individuals coping with blood vessel disorders or recent heart attack/stroke victims will make exceedingly rapid recoveries upon receiving treatment. Patients with pre-existing tumors or cancerous conditions may not be candidates for nicotine therapy due to its potent effects of tissue formation in tumors.
Despite nicotine’s curative powers, its legacy of merciless carnage through tobacco related illnesses overshadows its advantages. But it was not until recently, that technology may soon change the face of its name. It has inflicted the lives of many with it powerful addictive force, however, as technology continues to progress and as research continues to cultivate new discoveries, the drug that has taken the lives of many has a promising outlook for an opposite effect.